ACP6 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-15175-60, E-AB-15175-120, E-AB-15175-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ACP6

Target Synonym: Acid phosphatase 6; Acid phosphatase 6; lysophosphatidic; Acid phosphatase like 1; Acid phosphatase like protein 1; Acid phosphatase-like protein 1; ACP6; ACPL1; LPAP; Lysophosphatidic acid phosphatase 6; Lysophosphatidic acid phosphatase type 6; Lysophosphatidic acid phosphatase type 6 precursor; lysophosphatidic; PACPL1; PPA6

Research Areas: Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9NPH0

Background: Lysophosphatidic acid phosphatase type 6 (ACP6), also designated acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol. ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and exists as two isoforms as a result of alternative splicing events. The gene encoding ACP6 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease, familial adenomatous polyposis and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Concentration: 0.2 mg/mL

Immunogen: Recombinant protein of human ACP6

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW: 49kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only