Recombinant LRP1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: E-AB-81579-50, E-AB-81579-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: LRP1

Target Synonym: LRP1; A2MR; APOER; APR; CD91; IGFBP3R; KPA; LRP; LRP1A; TGFBR5

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC-P

Isotype: IgG

Clonality: Rabbit Monoclonal

Clone No.: R09-4E8

UNIProt ID: Q07954

Background: This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients.

Concentration: 300 μg/mL

Immunogen: A synthetic peptide of human LRP1

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification Method: Affinity Purified

Dilution: WB 1:1000-1:2000 IHC 1:20-1:100

Calculated MW: 85kDa

Observed MW: 85kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only