AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis, with an EC50 of 2.5 nM in cell assay.

Product information

CAS Number: 2239272-16-1

Molecular Weight: 404.39

Formula: C19H19F3N6O

Chemical Name: 2-[(3S)-3-methylmorpholin-4-yl]-N-{[2-(trifluoromethyl)pyridin-3-yl]methyl}pyrido[2,3-d]pyrimidin-4-amine

Smiles: C[C@H]1COCCN1C1N=C2N=CC=CC2=C(NCC2=CC=CN=C2C(F)(F)F)N=1

InChiKey: IZFVCNUAPFSNCO-LBPRGKRZSA-N

InChi: InChI=1S/C19H19F3N6O/c1-12-11-29-9-8-28(12)18-26-16-14(5-3-7-24-16)17(27-18)25-10-13-4-2-6-23-15(13)19(20,21)22/h2-7,12H,8-11H2,1H3,(H,24,25,26,27)/t12-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 125 mg/mL (309.11 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.