Dnmt3a Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12003-50, MB12003-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9Y6K1

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2 and DNMT3. DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Dnmt3a in Hela, A549Lysates using Dnmt3a antibody.

Bioworld Molecular Weight: Calculated MW: 102 kDa; Observed MW: 130 kDa

Specificity: IgG

Alternative Name: DNMT3A2; M.HsaIIIA; Dnmt3a; MCMT; DNA methyltransferase 3a

Immunogen: A synthetic peptide of human Dnmt3a

Conjugate: Unconjugated

Modification: Unmodified