OPRL1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8068-50, BS8068-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P41146

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200

Background: Endogenous opioid peptides and opiates like morphine mediate their cellular effects through membrane bound receptors. Three different types of opioid receptors have been identified, mu-type, delta-type and kappa-type. A fourth opioid receptor, KOR-3 (kappa-type opioid receptor, also designated ORL1- Opioid Receptor Like 1), has been identified. Though closely related genetically to the other opioid receptors, KOR-3 has a distinct pharmacological profile. Nociceptin, the neuropeptide which activates KOR-3, is structurally similar to the kappa-opioid peptide dynorphin A, but quite different in its mode of interaction with its receptor. KOR-3 is widely expressed in the nervous system, and is likely to modulate a broad range of physiological and behavioral functions.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: OPRL1 polyclonal antibody detects endogenous levels of OPRL1 protein.

Bioworld Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot (WB) analysis of OPRL1 polyclonal antibody

Alternative Name: Nociceptin receptor; Kappa-type 3 opioid receptor; KOR-3; Orphanin FQ receptor; OPRL1; OOR; ORL1

Immunogen: Recombinant full length Human OPRL1.

Conjugate: Unconjugated

Modification: Unmodified