PARP-2-IN-1 is a potent and selective PARP-2 inhibitor with an IC50 of 11.5 nM.

Product information

CAS Number: 2115698-83-2

Molecular Weight: 465.40

Formula: C21H19F4N5O3

Chemical Name: (3S)-N-{5-[(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)methyl]-2-fluoropyridin-3-yl}-1-(2,2,2-trifluoroethyl)pyrrolidine-3-carboxamide

Smiles: O=C1NC(=O)N(CC2=CN=C(F)C(=C2)NC(=O)[C@@H]2CN(CC(F)(F)F)CC2)C2=CC=CC=C12

InChiKey: JZKVDRXHUJSBJE-ZDUSSCGKSA-N

InChi: InChI=1S/C21H19F4N5O3/c22-17-15(27-18(31)13-5-6-29(10-13)11-21(23,24)25)7-12(8-26-17)9-30-16-4-2-1-3-14(16)19(32)28-20(30)33/h1-4,7-8,13H,5-6,9-11H2,(H,27,31)(H,28,32,33)/t13-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.