Recombinant Human SerpinB3/SCCA1 Protein (Human Cells, His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH033307-10, PKSH033307-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: SerpinB3; SCCA1

Target Synonym: Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; serine (or cysteine) proteinase inhibitor; clade B (ovalbumin); member 3; serpin peptidase inhibitor; clade B (ovalbumin); member 3; Squamous cell carcinoma antigen 1; T4-A; SCCA1; HsT1196; SCC; SCCA-1; SCCA-PD

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-6His

Accession: AAB20405.1

Background: Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).

Sequence: Met 1-Pro390

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 46.0 kDa

Observed MW: 41-50 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only