P2RY2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS7856-50, BS7856-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P41231

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: Nucleotides are emerging as important extracellular signaling molecules that mediate several effects, such as proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, P2X and P2Y. The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. The P2Y receptors are differentially expressed in several tissue types, such as heart, lung and brain. However, all P2Y receptors are expressed in leukocytes, which suggests a role for the P2Y receptor family in the activation of leukocytes and platelets in response to inflammation or vascular damage.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: P2RY2 polyclonal antibody detects endogenous levels of P2RY2 protein.

Bioworld Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot (WB) analysis of P2RY2 polyclonal antibody

Alternative Name: ATP receptor;
HP2U;
Human P2U nucleotide receptor mRNA complete cds;
MGC20088;
MGC40010;
P2RU1;
P2RY2;
P2RY2_HUMAN;
P2U;
P2U nucleotide receptor;
P2U purinoceptor 1;
P2U receptor 1;
P2U1;
P2UR;
P2Y purinoceptor 2;
P2Y2;
P2Y2R;
Purinergic receptor;
Purinergic receptor P2Y G protein coupled 2;
Purinergic receptor P2Y2;
Purinoceptor P2Y2;

Immunogen: Recombinant full length Human P2RY2.

Conjugate: Unconjugated

Modification: Unmodified