From the NYT bestselling author of Bel Canto and Run, a major and explosively ambitious new novel, set in the Amazonian jungle, both a gripping adventure story and a profound investigation of difficult human choices.

Marina Singh is a research scientist at Vogel, a pharmaceutical institute in Minnesota, inconveniently in love with her boss, Mr. Fox . When one of her colleagues is reported to have died while following up on the progress of a field team based in Brazil, Marina is dispatched by Mr. Fox to the Amazon to uncover the truth of his death. And his widow wants his effects. She travels to Manaus, then down into the Amazonian delta, deep into the dense, dark, insect-infested jungle. The research team is looking into the development of a new miracle drug that could revolutionize Western society. A local tribe has the bark of a certain tree, it yields a substance which allows them to conceive late into middle age: many of the women are getting pregnant into their sixties and seventies. The problem is that the team is taking too long: they have been silent for two years, and Marina has been tasked to find out what is holding back their progress. The second problem is more serious: the team is being headed up by the daunting figure of Marina Swenson, an eminent and fiercely uncompromising scientist who was once Marina’s colleague, and towards whom Marina has very complicated feelings.

What Marina learns will change her life. In a novel that is packed with amazing twists and surprises, Ann Patchett returns with immense confidence to a broad canvas, teeming with atmosphere and characters and rich with narrative. Remarkable events - fights with anacondas; encounters with cannibals; deaths; re-births - and profound moral decisions come together in a novel that will enthrall her many readers and fans, and is guaranteed to be a major bestseller.

• Paperback: 368 pages
• Publisher: Harper (February 7, 2023)
• ISBN-13: 978-0062049810