SAMHD1 (phospho-Thr592) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES13204-50, ES13204-100

Citations, Manuals and MSDS Available upon request.

Background: SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010],

Alternate Name: SAM domain and HD domain-containing protein 1 (EC 3.1.4.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5)

Source: Rabbit

Applications: WB

Dilution: WB 1:1000-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized phosho peptide around human SAMHD1 (Thr592)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 72kD

Human Gene ID: 25939

Human SWISS Prot NO: Q9Y3Z3

Subcellular Location: Nucleus. Chromosome. Localizes to sites of DNA double-strand breaks in response to DNA damage.

Research Use Only